QUANTAMATRIX INCORPORATED

SEOUL

Unclaimed

Subcontracting experience

1 record from government sources. Past participation is not evidence of current teaming interest.

Role	Agency	Description	Vehicle	Obligated	Action date	Period
Subcontractor	Department of Health and Human Services	QMAP (QUICK MULTIPLEXED ASSAY PLATFORM) IS A CHEAP, FAST, ACCURATE, AND HIGHLY SCALABLE FULLY AUTOMATED SYSTEM FOR NEONATAL SEPSIS SCREENING. IT CAN OFFER BROAD-SPECTRUM ANALYSIS OF MOLECULAR MARKERS REPRESENTING PATHOGEN SPECIES AND ANTIMICROBIAL RESISTANCE THROUGH A SINGLE-POT REACTION. THIS ENABLES RAPID DIAGNOSIS, PROVIDING ACCURATE RESULTS WITHIN 6 HOURS FROM LESS THAN 2 ML OF WHOLE BLOOD. THE SYSTEM EMPLOYS GRAPHICALLY ENCODED MICRODISKS, EACH ENGINEERED TO DETECT SPECIFIC ID/AST GENE MOLECULES THROUGH THE ATTACHMENT OF COMPLEMENTARY DNA PROBES, WHICH ARE SUBSEQUENTLY POOLED FOR EACH ASSAY. THE SYSTEM IS HIGHLY SCALABLE AND MULTIPLEXED, ENABLING THE INTEGRATION OF BOTH PATHOGEN ID AND AST AT A SINGLE RUN. EACH ID OR AST SPECIFIC MICRODISKS CAN BE MASS-PRODUCED AT A LOW COST. THE ONE-POT APPROACH ALLOWS PARALLEL DETECTION OF 71 GENES(ID 44 GENES AND AST 27 GENES) WITH MINIMAL USAGE OF REAGENTS AND ASSOCIATED KITS. COMPARED TO EXISTING TECHNOLOGIES, OVERALL REAGENT COSTS CAN BE REDUCED BY 4 TO 5- FOLD, WHILE ACHIEVING 2 TO 10 TIMES GREATER ID/AST GENE COVERAGE, MAKING IT IDEAL FOR A COMPREHENSIVE NEONATAL SEPSIS SCREENING PLATFORM THAT IS ALSO AFFORDABLE FOR LMICS. WITH MINIMAL SAMPLE PREPARATION AND OUR ONE-POT REACTION DESIGN, EACH STEP IS SIMPLIFIED, MINIMIZING THE RISK OF SAMPLE DILUTION OR BACTERIAL LOSS DURING TRANSFER, DISTRIBUTION, OR REACTIONS. THIS CAN POTENTIALLY REDUCE THE REQUIRED BLOOD SAMPLE VOLUME BY MORE THAN 50% COMPARED TO CONVENTIONAL DIAGNOSTICS AND ALSO ENHANCE THE SENSITIVITY OF ASSAY. FURTHERMORE, THE SYSTEM ULTIMATELY ENABLES THE DETECTION OF OVER 100 DISTINCT PROBES BY INCORPORATING ADDITIONAL TYPES OF MICRODISKS. THIS FLEXIBILITY ALLOWS QMAP TO EXPAND ITS PANEL LIBRARY TO INCLUDE NEW PATHOGENS OR AMR GENES, PROVIDING AN ADAPTABLE SOLUTION FOR EVOLVING CLINICAL REQUIREMENTS. MANY COMPANIES HAVE DEVELOPED METHODS(FLUORESCENCE-BASED PRINCIPLE, NMR-BASED PRINCIPLE, ELECTROCHEMICAL-BASED PRINCIPLE) TO MAXIMIZE THE DETECTION COVERAGE FOR COMPREHENSIVE PROFILING OF PATHOGEN SPECIES AND ANTIMICROBIAL RESISTANCE. HOWEVER, THE NUMBER OF MOLECULES BEING ANALYZED IN SINGLE WELL HAS BEEN SEVERELY LIMITED BY THE TYPE OF DETECTION SIGNAL, SPATIAL SEPARATION REQUIREMENTS (COMPARTMENTALIZATION), OR THE INCREASING CONSUMABLES AND EQUIPMENT COSTS. THE QMAP TECHNOLOGY OVERCOMES THE LIMITATIONS OF TARGET MULTIPLEXITY, OPERATING ENTIRELY IN A SINGLE WELL WHILE MINIMIZING SAMPLE LOSS, DILUTION, COMPLEXITY OF OPERATION, AND REAGENT USAGE. QMAP ENABLES ONE-POT SIMULTANEOUS SCREENING OF OVER 100 UNIQUE TARGETS, DEMONSTRATING STRONG POTENTIAL FOR NEONATAL SEPSIS DIAGNOSTICS, WHERE RAPID AND COMPREHENSIVE PATHOGEN IDENTIFICATION AND RESISTANCE PROFILING ARE CRITICAL. KC4096 Parent award context Parent award agency: Department of Health and Human Services · Office of Assistant Secretary for Preparedness and Response Parent award NAICS: 541714 Parent award performance state: MA Parent award description: CARB-X GLOBAL ANTIBACTERIAL ACCELERATOR OTA View parent award on USAspending	—	$998,055	Aug 18, 2025	— – —

Contract vehicles are shown only when present in the source record. Linked award numbers and vehicles open the authoritative record on USAspending.gov.