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AFRIMS THAI COMPONENT
BANGKOK
Unclaimed
Small Business
Prime contracting experience
4 records from government sources. Past participation is not evidence of current teaming interest.
| Role | Agency | Description | Vehicle | Obligated | Action date | Period |
|---|---|---|---|---|---|---|
| Prime | Department of Defense Defense Health Agency | INFECTIOUS DISEASE SURVEILLANCE | — | $405,418 | Sep 15, 2025 | Sep 23, 2024 – Sep 22, 2026 |
| Prime | Department of Defense Defense Health Agency | SURVEILLANCE OF PATHOGENS IN BORDER PROVINCE ROYAL THAI ARMY HOSPITALS ARMED FORCES RESEARCH INSTITUTE OF MEDICAL SCIENCES | — | $521,565 | Dec 5, 2024 | Sep 24, 2019 – Sep 24, 2024 |
| Prime | Department of Defense Department of the Army | IGF::OT::IGF LABOR BASE PERIOD | — | $1,722,142 | May 15, 2024 | Sep 30, 2015 – Sep 29, 2020 |
| Prime | Department of Defense Defense Health Agency | GEIS SURVEILLANCE IN NEPAL AND THAILAND FOR AFRIMS ON BEHALF OF WALTER REED ARMY INSTITUTE OF RESEARCH | — | $661,032 | Sep 7, 2023 | Sep 24, 2020 – Sep 29, 2024 |
Contract vehicles are shown only when present in the source record. Linked award numbers and vehicles open the authoritative record on USAspending.gov.
Subcontracting experience
1 record from government sources. Past participation is not evidence of current teaming interest.
| Role | Agency | Description | Vehicle | Obligated | Action date | Period |
|---|---|---|---|---|---|---|
| Subcontractor | Department of Health and Human Services | STATEMENT OF WORK
TITLE: DIAGNOSTIC PERFORMANCE OF SEROLOGICAL ASSAYS FOR DETECTION OF OPISTHORCHIS VIVERRINI INFECTION
BACKGROUND:
OPISTHORCHIASIS IS A FOODBORNE TREMATODE INFECTION CAUSED BY THE OPISTHORCHIS VIVERRINI (OV).
THE IMPORTANCE OF OV INFECTION IS THAT CHRONIC OPISTHORCHIASIS CAN CAUSE AN ADVANCED PERIDUCTAL FIBROSIS IN HEPATOBILIARY SYSTEM. THIS ADVANCED HEPATOBILIARY PATHOLOGY CAN LEAD TO AN INTRAHEPATIC CHOLANGIOCARCINOMA (CCA). THEREFORE, PREVENTION AND ERADICATION OF OV BY SCREENING, DIAGNOSIS, AND TREATMENT OF OV INFECTION ARE AN IMPORTANT STRATEGY TO DECREASE THE MORBIDITY AND MORTALITY FROM CCA IN THE POPULATION.
THE CURRENT GOLD STANDARD TEST FOR DIAGNOSIS OV INFECTION IS FECAL EXAMINATION USING THE FORMALIN ETHYL ACETATE CONCENTRATION TECHNIQUE (FECT). HOWEVER, FECAL EXAMINATION BY FECT HAS SEVERAL LIMITATIONS. FOR INSTANCE, LOW-INTENSITY OF OV INFECTION CANNOT BE DETECTED BY THIS METHOD. THUS EXTENSIVE FECAL SAMPLING OVER DAYS IS REQUIRED TO INCREASE THE SENSITIVITY OF THE TEST. MOREOVER, OV EGGS ARE FREQUENTLY MISTAKEN WITH EGGS FROM AN INFECTION WITH MINUTE INTESTINAL FLUKES THAT NEEDS AN EXPERT MICROSCOPIST TO DIFFERENTIATE OV EGGS FROM OTHER MINUTE INTESTINAL FLUKES.
THUS, THE NEW DIAGNOSTIC TEST IS NECESSARY TO INCREASE THE LIKELIHOOD OF DIAGNOSIS OV INFECTION, ESPECIALLY IN THE PERSONS HAVING LIGHT INFECTION. CURRENTLY, A SEROLOGICAL TEST DETECTING OV IGG ANTIBODIES USING ELISA AND POINT-OF-CARE LATERAL FLOW ASSAY HAVE BEEN DEVELOPED TO IDENTIFY INDIVIDUALS WHO CURRENTLY OR PREVIOUSLY HAVE OV INFECTION. HOWEVER, THE PERFORMANCE OF THE ELISA AND POINT-OF-CARE LATERAL FLOW ASSAY HAS NOT BEEN INVESTIGATED IN THE GENERAL POPULATION THAT IS THE TARGETED POPULATION FOR SCREENING OV INFECTION.
PURPOSE/GOALS:
1. TO ASSESS THE PERFORMANCE OF THE ELISA TEST FOR DIAGNOSIS OF OV INFECTION AMONG PEOPLE LIVING IN NAMPHONG DISTRICT, KHON KAEN PROVINCE, THAILAND
2. TO ASSESS THE PERFORMANCE OF THE LATERAL FLOW ASSAY FOR DIAGNOSIS OF OV INFECTION AMONG PEOPLE LIVING IN NAMPHONG DISTRICT, KHON KAEN PROVINCE, THAILAND
SCOPE:
LABORATORY AGREES TO:
1. DEVELOP THE RESEARCH PROTOCOL
2. SUBMIT THE PROTOCOL TO WRAIR AND LOCAL IRB
3. CONDUCT THE COMMUNITY SURVEY IN KHON KAEN PROVINCE, THAILAND
4. COLLECT THE SERUM AND STOOL SPECIMENS FROM STUDY€„¢S PARTICIPANTS
5. TRANSFER THE SERUM SPECIMENS TO THE COMPANY IN U.S.
6. PERFORM THE STOOL EXAMINATION TO DIAGNOSIS OV INFECTION
7. PROVIDE MONTHLY UPDATES VIA EMAIL ON THE STATUS OF THE PROJECT
COOPERATOR AGREES TO:
1. PERFORM THE ELISA TESTS AND LATERAL FLOW ASSAY
2. PROVIDE CONSULTATION TO AFRIMS ABOUT STOOL EXAMINATION FOR DIAGNOSIS OF OV INFECTION
THE PARTIES AGREE TO:
1. JOINTLY ANALYZE DATA
2. PREPARE RESEARCH REPORT
3. COOPERATE ON ANY PUBLICATIONS REGARDING THE RESEARCH PROJECT IN ACCORDANCE WITH SECTIONS 9.5 AND 9.6. W81XWH-23-0122 Parent award context Parent award agency: Department of Health and Human Services · National Institutes of Health Parent award NAICS: 541715 Parent award performance state: MA Parent award description: TOPIC 388: IN VITRO DIAGNOSTIC FOR THE LIVER FLUKES OPISTHORCHIS VIVERRINI AND CLONORCHIS SINENSI View parent award on USAspending | — | $71,007 | Feb 22, 2023 | — – — |
Contract vehicles are shown only when present in the source record. Linked award numbers and vehicles open the authoritative record on USAspending.gov.
Agencies supported
- Department of DefenseGov-sourced