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LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE
LONDON, WC1E7
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Subcontracting experience
4 records from government sources. Past participation is not evidence of current teaming interest.
| Role | Agency | Description | Vehicle | Obligated | Action date | Period |
|---|---|---|---|---|---|---|
| Subcontractor | Department of Health and Human Services | THE SCOPE OF THIS SUBAWARD IS TO ISOLATE CELLS FROM THE TISSUES OF DECEASED PATIENTS AND THEN EXAMINE CELL SUBSET AND FUNCTION WITHIN THE TISSUES OF ACTIVE TB, LATENT TB AND UNINFECTED INDIVIDUALS. SPECIFICALLY IN THIS YEAR OF THE STUDY (YEAR 5) WE WILL RECRUIT AN ADDITIONAL 60 POST-MORTEM SUBJECTS AND CATEGORIZE THEIR TB DISEASE STATE.
€¢ WE WILL UNDERTAKE IMMUNOLOGY STUDIES TO EXAMINE CELL SUBSET AND FUNCTION IN THE TISSUES OF DECEASED ACTIVE TB, LATENT TB AND UNINFECTED PATIENTS.
€¢ WE WILL CONTINUE DEFINE THE GRANULOMA ANATOMY IN THE DIFFERENT DISEASE STATES; SHIPPING TISSUE SAMPLES TO SCRI/UW IN SEATTLE TO STUDY HETEROGENEITY OF THE IMMUNE LANDSCAPE IN GRANULOMAS AND TISSUES USING MULTIPARAMETER CONFOCAL IMAGING AND SPATIAL GENOMICS.
€¢ WE WILL FURTHER INTERROGATE DIFFERENCES WITHIN IDENTIFIED SUBCLINICAL TB SUBJECTS, EXAMINING PHENOTYPE AND FUNCTION OF THE CD4+/KLRG1+/CD27- T CELL SUBSET. FINALLY WE WILL ALSO UNDERTAKE CD45 INTRAVITAL STAINING, ESTABLISHING THE STAINING PROCEDURE AND DETERMINING IF THE CD4+/KLRG1+/CD27- T CELL SUBSET IS EMBEDDED WITHIN THE VASCULATURE, OR ARE TISSUE-RESIDENT 13211SUB Parent award context Parent award agency: Department of Health and Human Services · National Institutes of Health Parent award NAICS: 541714 Parent award performance state: WA Parent award description: IMMUNE MECHANISMS OF PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS CENTER (IMPAC-TB) View parent award on USAspending | — | $499,937 | Dec 31, 2023 | — – — |
| Subcontractor | Department of Health and Human Services | WE WILL CONDUCT A MIXED METHODS STUDY PROCEEDING IN FOUR PHASES. FIRST, WE WILL RAPIDLY DEVELOP TWO SURVEY INSTRUMENTS TO MEASURE AS PRACTICES, RESOURCES AND NEEDS AT BOTH THE NATIONAL-LEVEL AND HOSPITAL-LEVEL. SECOND, WE WILL ADMINISTER OUR HOSPITAL-LEVEL SURVEY AT ABOUT 25 HOSPITALS AND OUR NATIONAL-LEVEL SURVEY TO REPRESENTATIVES FROM THE MINISTRY OF HEALTH ACROSS BOTSWANA, SOUTH AFRICA AND ZIMBABWE. WE WILL SUPPLEMENT HOSPITAL-LEVEL SURVEY DATA WITH FACILITY-LEVEL ANTIBIOTIC USE DATA ACROSS SELECTED HOSPITALS IN BOTSWANA. THIRD, WE WILL CONDUCT AN IN-DEPTH QUALITATIVE CASE STUDY OF SELECTED HOSPITALS IN BOTSWANA TO GAIN A DEEPER UNDERSTANDING OF FACTORS THAT SHAPE IMPLEMENTATION OF ASP FROM THE PERSPECTIVE OF KEY STAKEHOLDERS. FOURTH, WE WILL CREATE AN AS IMPLEMENTATION TOOLKIT AND USE IT TO INFORM A STAKEHOLDER-ENGAGED CAPACITY BUILDING PROCESS IN BOTSWANA 583437 Parent award context Parent award agency: Department of Health and Human Services · Centers for Disease Control and Prevention Parent award NAICS: 541715 Parent award performance state: GA Parent award description: FY 21 BAA TOPIC 4.6 - PENNSYLVANIA View parent award on USAspending | — | $24,988 | Sep 23, 2022 | — – — |
| Subcontractor | Department of Health and Human Services | STEPHEN COSE WILL LEAD THE HUMAN POST-MORTEM PROJECT IN ENTEBBE, UGANDA. HAVING ESTABLISHED FEASIBILITY STUDIES IN YEARS 1 & 2, HE WILL NOW PERFORM IMMUNOLOGY STUDIES TO EXAMINE CELL SUBSET AND FUNCTION IN THE TISSUES OF DECEASED ACTIVE TB, LATENT TB AND UNINFECTED PATIENTS. IN YEAR 3 HE WILL ALSO PERFORM STUDIES TO DEFINE THE GRANULOMA ANATOMY IN THE DIFFERENT DISEASE STATES AND IDENTIFY THE LOCATION OF MTB BACILLI IN THE GRANULOMA AND TISSUES. 12707SUB Parent award context Parent award agency: Department of Health and Human Services · National Institutes of Health Parent award NAICS: 541714 Parent award performance state: WA Parent award description: IMMUNE MECHANISMS OF PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS CENTER (IMPAC-TB) View parent award on USAspending | — | $198,689 | May 31, 2022 | — – — |
| Subcontractor | Agency for International Development | PEDIATRIC EYE HEALTH PROGRAM TO PREVENT BLINDNESS AND EARLY DEATH IN YOUNG CHILDREN IN TANZANIA BY SCALING UP THE EARLY DETECTION OF CLINICALLY SIGNIFICANT EYE DISEASES THROUGH TRAINING PRIMARY CHILD HEALTH CARE HEALTH WORKERS IN RED REFLEX TESTING AND REFERRAL FOR CLINICAL CARE AND REHABILITATION. CBP057-LSHTM Parent award context Parent award agency: Agency for International Development · Agency for International Development Parent award NAICS: 541990 Parent award description: THIS IS A COST-PLUS-FIXED FEE (CPFF) COMPLETION TYPE CONTRACT FOR TECHNICAL AND PROFESSIONAL SERVICES TO SUPPORT USAID'S CONGRESSIONALLY-MANDATED CHILD BLINDNESS DIRECTIVE. THE CONTRACTOR MUST PERFORM THE SERVICES SET FORTH IN THIS CONTRACT AT PRICES CONSISTENT WITH SECTION B OF THIS CONTRACT. View parent award on USAspending | — | $163,732 | Apr 29, 2022 | — – — |
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