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EVOTEC INTERNATIONAL GMBH
HAMBURG, 22419
UnclaimedClaim this profile (free)
Subcontracting experience
2 records from government sources. Past participation is not evidence of current teaming interest.
| Role | Agency | Description | Vehicle | Obligated | Action date | Period |
|---|---|---|---|---|---|---|
| Subcontractor | Department of Health and Human Services | EVOTEC IS POISED TO START, UNDER CARB-X FUNDING, A NEW PROGRAM. THIS PROGRAM IS AT LEAD-TO-CANDIDATE STAGE AND AIMS AT DELIVERING AN IV-ADMINISTERED BROAD-SPECTRUM ANTIBACTERIAL DRUG CANDIDATE TO ADDRESS SEVERE HOSPITAL INFECTIONS CAUSED BY MULTI-DRUG RESISTANT (MDR) PATHOGENS. THE CORRESPONDING COMPOUNDS CONSTITUTE A NEW ANTIBACTERIAL CLASS THAT SIMULTANEOUSLY TARGETS TWO ESSENTIAL, WELL VALIDATED BACTERIAL ENZYMES. HOWEVER, THEY ACT BY A NEW MODE OF ACTION BECAUSE THEY BIND TO SITES THAT ARE NOT TARGETED BY CURRENTLY MARKETED ANTIBACTERIALS. THIS CLASS HAS SEVERAL BENEFICIAL PROPERTIES, INCLUDING A VERY BROAD-SPECTRUM OF BOTH GRAM-POSITIVE AND GRAM-NEGATIVE PATHOGENS, COVERING IN PARTICULAR MOST OF THE PROBLEMATIC MDR STRAINS. IN ADDITION, THE CLASS IS NOTED FOR ITS HIGH ANTIBACTERIAL POTENCY AND VERY LOW PROPENSITY TO SELECT RESISTANT STRAINS DUE TO THE UNIQUE DUAL-TARGETING MECHANISM. THE LEAD COMPOUNDS HAVE PERFORMED WELL IN EFFICACY AND SAFETY STUDIES. THE GOAL OF THE EVOTEC, CARB-X FUNDED PROGRAM IS TO COMPLETE THE OPTIMIZATION OF THE SERIES, IDENTIFY PRE-CANDIDATES AND ADVANCE THE MOST PROMISING COMPOUND INTO CLINICAL STUDIES. OVERALL, THIS NEW PROGRAM HAS POTENTIAL TO DELIVER TO THE CLINIC A NOVEL MODE OF ACTION, BROAD-SPECTRUM ANTIBACTERIAL DRUG, A MAJOR EVENT IN THE FIELD SINCE DECADES. 4500004468 Parent award context Parent award agency: Department of Health and Human Services · Office of Assistant Secretary for Preparedness and Response Parent award NAICS: 541714 Parent award performance state: MA Parent award description: CARB-X GLOBAL ANTIBACTERIAL ACCELERATOR OTA View parent award on USAspending | — | $23,385 | May 25, 2023 | — – — |
| Subcontractor | Department of Health and Human Services | EVOTEC IS POISED TO START, UNDER CARB-X FUNDING, A NEW PROGRAM. THIS PROGRAM IS AT LEAD-TO-CANDIDATE STAGE AND AIMS AT DELIVERING AN IV-ADMINISTERED BROAD-SPECTRUM ANTIBACTERIAL DRUG CANDIDATE TO ADDRESS SEVERE HOSPITAL INFECTIONS CAUSED BY MULTI-DRUG RESISTANT (MDR) PATHOGENS. THE CORRESPONDING COMPOUNDS CONSTITUTE A NEW ANTIBACTERIAL CLASS THAT SIMULTANEOUSLY TARGETS TWO ESSENTIAL, WELL VALIDATED BACTERIAL ENZYMES. HOWEVER, THEY ACT BY A NEW MODE OF ACTION BECAUSE THEY BIND TO SITES THAT ARE NOT TARGETED BY CURRENTLY MARKETED ANTIBACTERIALS. THIS CLASS HAS SEVERAL BENEFICIAL PROPERTIES, INCLUDING A VERY BROAD-SPECTRUM OF BOTH GRAM-POSITIVE AND GRAM-NEGATIVE PATHOGENS, COVERING IN PARTICULAR MOST OF THE PROBLEMATIC MDR STRAINS. IN ADDITION, THE CLASS IS NOTED FOR ITS HIGH ANTIBACTERIAL POTENCY AND VERY LOW PROPENSITY TO SELECT RESISTANT STRAINS DUE TO THE UNIQUE DUAL-TARGETING MECHANISM. THE LEAD COMPOUNDS HAVE PERFORMED WELL IN EFFICACY AND SAFETY STUDIES. THE GOAL OF THE EVOTEC, CARB-X FUNDED PROGRAM IS TO COMPLETE THE OPTIMIZATION OF THE SERIES, IDENTIFY PRE-CANDIDATES AND ADVANCE THE MOST PROMISING COMPOUND INTO CLINICAL STUDIES. OVERALL, THIS NEW PROGRAM HAS POTENTIAL TO DELIVER TO THE CLINIC A NOVEL MODE OF ACTION, BROAD-SPECTRUM ANTIBACTERIAL DRUG, A MAJOR EVENT IN THE FIELD SINCE DECADES. 4500004468 Parent award context Parent award agency: Department of Health and Human Services · Office of Assistant Secretary for Preparedness and Response Parent award NAICS: 541714 Parent award performance state: MA Parent award description: CARB-X GLOBAL ANTIBACTERIAL ACCELERATOR OTA View parent award on USAspending | — | $25,000 | Dec 22, 2022 | — – — |
Contract vehicles are shown only when present in the source record. Linked award numbers and vehicles open the authoritative record on USAspending.gov.
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