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ACME BIOSCIENCE, INC.
PALO ALTO, CA, 94303
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Subcontracting experience
5 records from government sources. Past participation is not evidence of current teaming interest.
| Role | Agency | Description | Vehicle | Obligated | Action date | Period |
|---|---|---|---|---|---|---|
| Subcontractor | Department of Health and Human Services | THE MEDICINAL CHEMISTRY FOCUS ON PI4K IS TO IDENTIFY A NOVEL SERIES OF BACK-UP COMPOUNDS THAT ARE DIVERSE WITH OFF-TARGET TOXICITY AS WELL AS PHARMACOKINETIC PROPERTIES. ACME IS BEST SITED TO PERFORM THIS WORK GIVEN THEIR PREVIOUS EXPERIENCE IN SYNTHESIZING A LARGE A RANGE OF PI4K MOLECULES IN A TIMELY FASHION. THE COMPANY WILL SYNTHESIZE CHEMICALS THAT ARE DESIGNED BY THE STANFORD MEDICINAL CHEMISTS. THE SCOPE OF CHEMISTRY ACTIVITIES: TYPICAL ACTIVITIES INCLUDE SYNTHESIS OF FOCUSED COMPOUND LIBRARIES (TYPICALLY 20-200 COMPOUNDS PER LIBRARY) ON A SCALE OF 10-50 MG AND PURITY OF >95%. PROVIDE RELEVANT ANALYTICAL DATA INCLUDING 1H, 13C NMR AND LCMS. SYNTHESIS (TYPICALLY >50 MG) OF ANALOGS OF EACH STRUCTURE TO SUPPORT LEAD OPTIMIZATION AND LEAD SERIES IDENTIFICATION ACTIVITIES. SYNTHESIS OF KEY REFERENCE COMPOUNDS IN THE 0.5-5 G RANGE AND A PURITY OF ~95-98% (>98% WHEN RELEVANT). SYNTHESIS OF KEY INTERMEDIATES ON 5-50 G SCALE AND A PURITY OF ~95%. SCALE-UP OF SELECTED COMPOUNDS FOR ADVANCED IN-VIVO STUDIES ON A SCALE OF 5-50 G AND PURITY OF 95% (>98% WHEN RELEVANT). DEVISING CHEMICAL SYNTHETIC ROUTES WHEN NECESSARY. TECHNICAL JUSTIFICATION WHEN FACTORING IN THE ANTICIPATED EXTRA FEES AND LACK OF CLOSE PROXIMITY, COMBINED WITH A LONG- STANDING TRACK RECORD OF PRODUCTIVE AND COST-EFFECTIVE WORK DONE BY ACME ON OUR BEHALF, THEY WERE FELT TO BE THE OVERALL BEST VALUE. 63464514-184638 Parent award context Parent award agency: Department of Health and Human Services · National Institutes of Health Parent award NAICS: 541715 Parent award performance state: CA Parent award description: COVID-19. TO DEVELOP SMALL SYNTHETIC CHEMICAL MOLECULES AS BROADLY ACTIVE ANTIVIRAL FOR THE TREATMENT OF VIRAL INFECTIONS. View parent award on USAspending | — | $245,200 | Jul 1, 2025 | — – — |
| Subcontractor | Department of Health and Human Services | THE MEDICINAL CHEMISTRY FOCUS ON PI4K IS TO IDENTIFY A NOVEL SERIES OF BACK-UP COMPOUNDS THAT ARE DIVERSE WITH OFF-TARGET TOXICITY AS WELL AS PHARMACOKINETIC PROPERTIES. ACME IS BEST SITED TO PERFORM THIS WORK GIVEN THEIR PREVIOUS EXPERIENCE IN SYNTHESIZING A LARGE A RANGE OF PI4K MOLECULES IN A TIMELY FASHION. THE COMPANY WILL SYNTHESIZE CHEMICALS THAT ARE DESIGNED BY THE STANFORD MEDICINAL CHEMISTS. THE SCOPE OF CHEMISTRY ACTIVITIES: TYPICAL ACTIVITIES INCLUDE SYNTHESIS OF FOCUSED COMPOUND LIBRARIES (TYPICALLY 20-200 COMPOUNDS PER LIBRARY) ON A SCALE OF 10-50 MG AND PURITY OF >95%. PROVIDE RELEVANT ANALYTICAL DATA INCLUDING 1H, 13C NMR AND LCMS. SYNTHESIS (TYPICALLY >50 MG) OF ANALOGS OF EACH STRUCTURE TO SUPPORT LEAD OPTIMIZATION AND LEAD SERIES IDENTIFICATION ACTIVITIES. SYNTHESIS OF KEY REFERENCE COMPOUNDS IN THE 0.5-5 G RANGE AND A PURITY OF ~95-98% (>98% WHEN RELEVANT). SYNTHESIS OF KEY INTERMEDIATES ON 5-50 G SCALE AND A PURITY OF ~95%. SCALE-UP OF SELECTED COMPOUNDS FOR ADVANCED IN-VIVO STUDIES ON A SCALE OF 5-50 G AND PURITY OF 95% (>98% WHEN RELEVANT). DEVISING CHEMICAL SYNTHETIC ROUTES WHEN NECESSARY. TECHNICAL JUSTIFICATION WHEN FACTORING IN THE ANTICIPATED EXTRA FEES AND LACK OF CLOSE PROXIMITY, COMBINED WITH A LONG- STANDING TRACK RECORD OF PRODUCTIVE AND COST-EFFECTIVE WORK DONE BY ACME ON OUR BEHALF, THEY WERE FELT TO BE THE OVERALL BEST VALUE. 63464514-184638 Parent award context Parent award agency: Department of Health and Human Services · National Institutes of Health Parent award NAICS: 541715 Parent award performance state: CA Parent award description: COVID-19. TO DEVELOP SMALL SYNTHETIC CHEMICAL MOLECULES AS BROADLY ACTIVE ANTIVIRAL FOR THE TREATMENT OF VIRAL INFECTIONS. View parent award on USAspending | — | $186,400 | Jul 1, 2025 | — – — |
| Subcontractor | Department of Health and Human Services | THE MEDICINAL CHEMISTRY FOCUS ON PI4K IS TO IDENTIFY A NOVEL SERIES OF BACK-UP COMPOUNDS THAT ARE DIVERSE WITH OFF-TARGET TOXICITY AS WELL AS PHARMACOKINETIC PROPERTIES. ACME IS BEST SITED TO PERFORM THIS WORK GIVEN THEIR PREVIOUS EXPERIENCE IN SYNTHESIZING A LARGE A RANGE OF PI4K MOLECULES IN A TIMELY FASHION. THE COMPANY WILL SYNTHESIZE CHEMICALS THAT ARE DESIGNED BY THE STANFORD MEDICINAL CHEMISTS. THE SCOPE OF CHEMISTRY ACTIVITIES: TYPICAL ACTIVITIES INCLUDE SYNTHESIS OF FOCUSED COMPOUND LIBRARIES (TYPICALLY 20-200 COMPOUNDS PER LIBRARY) ON A SCALE OF 10-50 MG AND PURITY OF >95%. PROVIDE RELEVANT ANALYTICAL DATA INCLUDING 1H, 13C NMR AND LCMS. SYNTHESIS (TYPICALLY >50 MG) OF ANALOGS OF EACH STRUCTURE TO SUPPORT LEAD OPTIMIZATION AND LEAD SERIES IDENTIFICATION ACTIVITIES. SYNTHESIS OF KEY REFERENCE COMPOUNDS IN THE 0.5-5 G RANGE AND A PURITY OF ~95-98% (>98% WHEN RELEVANT). SYNTHESIS OF KEY INTERMEDIATES ON 5-50 G SCALE AND A PURITY OF ~95%. SCALE-UP OF SELECTED COMPOUNDS FOR ADVANCED IN-VIVO STUDIES ON A SCALE OF 5-50 G AND PURITY OF 95% (>98% WHEN RELEVANT). DEVISING CHEMICAL SYNTHETIC ROUTES WHEN NECESSARY. TECHNICAL JUSTIFICATION WHEN FACTORING IN THE ANTICIPATED EXTRA FEES AND LACK OF CLOSE PROXIMITY, COMBINED WITH A LONG- STANDING TRACK RECORD OF PRODUCTIVE AND COST-EFFECTIVE WORK DONE BY ACME ON OUR BEHALF, THEY WERE FELT TO BE THE OVERALL BEST VALUE. 63464514-184638 Parent award context Parent award agency: Department of Health and Human Services · National Institutes of Health Parent award NAICS: 541715 Parent award performance state: CA Parent award description: COVID-19. TO DEVELOP SMALL SYNTHETIC CHEMICAL MOLECULES AS BROADLY ACTIVE ANTIVIRAL FOR THE TREATMENT OF VIRAL INFECTIONS. View parent award on USAspending | — | $116,575 | Jun 12, 2024 | — – — |
| Subcontractor | Department of Health and Human Services | SYNTHETIC ORGANIC CHEMISTRY USING CHEMICALS DESIGNED BY STANFORD MEDICINAL CHEMISTS. THE SERVICES TO BE PROVIDED BY ACME UNDER THIS AGREEMENT MAY INCLUDE, BUT NOT BE LIMITED TO: CUSTOM SYNTHESIS, LIBRARY GENERATION, MEDICINAL CHEMISTRY, COMPUTATIONAL CHEMISTRY, AND OTHER CONTRACT RESEARCH SERVICES MUTUALLY AGREED TO BY THE PARTIES. 62502201-184638 Parent award context Parent award agency: Department of Health and Human Services · National Institutes of Health Parent award NAICS: 541715 Parent award performance state: CA Parent award description: COVID-19. TO DEVELOP SMALL SYNTHETIC CHEMICAL MOLECULES AS BROADLY ACTIVE ANTIVIRAL FOR THE TREATMENT OF VIRAL INFECTIONS. View parent award on USAspending | — | $91,000 | Mar 27, 2023 | — – — |
| Subcontractor | Department of Health and Human Services | "SYNTHETIC ORGANIC CHEMISTRY USING CHEMICALS DESIGNED BY STANFORD MEDICINAL CHEMISTS. THE SERVICES TO BE PROVIDED BY ACME UNDER THIS AGREEMENT MAY INCLUDE, BUT NOT BE LIMITED TO: CUSTOM SYNTHESIS, LIBRARY GENERATION, MEDICINAL CHEMISTRY, COMPUTATIONAL CHEMISTRY, AND OTHER CONTRACT RESEARCH SERVICES MUTUALLY AGREED TO BY THE PARTIES." 62502201-184638 Parent award context Parent award agency: Department of Health and Human Services · National Institutes of Health Parent award NAICS: 541715 Parent award performance state: CA Parent award description: COVID-19. TO DEVELOP SMALL SYNTHETIC CHEMICAL MOLECULES AS BROADLY ACTIVE ANTIVIRAL FOR THE TREATMENT OF VIRAL INFECTIONS. View parent award on USAspending | — | $91,221 | Jan 27, 2022 | — – — |
Contract vehicles are shown only when present in the source record. Linked award numbers and vehicles open the authoritative record on USAspending.gov.
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