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Health Science Futures (HSF) Mission Office Innovative Solutions Opening (ISO)
National Institutes of Health · ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
Respond by: Mar 5, 2029, 11:59 PM UTC−5858 days left
From SAM.gov's public data file generated Oct 29, 2026, 3:30 AM UTC; newest notice posted Oct 29, 2026; loaded into FedSub Oct 29, 2026, 5:46 AM UTC
Notice facts
Source: SAM.gov Contract Opportunities public data file
- Solicitation number
- ARPA-H-SOL-24-104
- Notice type
- Solicitation
- Posted
- Mar 14, 2024 · Amended Jan 8, 2026
- Response date
- Respond by Mar 5, 2029, 11:59 PM UTC−5
- Set-aside
- None stated
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences
- Product or service code
- AN13
- Place of performance
- USA
- Contracting office
- ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H) (75N992)Washington, DC 20005
- Agency
- Department of Health and Human Services · National Institutes of Health
Past prime awardees
Source: Award history, not a list of bidders on this notice
Past prime awardees · award history, not a list of bidders on this notice
19 companies held prime contracts from this office under NAICS 541715; 3 of them reported first-tier subawards to companies with NAICS 541715 in FedSub's records.
- THE MITRE CORPORATION · Reported first-tier subawards to 90 companies with NAICS 541715 in FedSub's records (latest Aug 2026).
18 more past prime awardees on Professional
Description
Source: SAM.gov Contract Opportunities public data file
This ISO seeks solution summaries and proposal submissions for projects that fall within the general scope of the ARPA-H Health Science Futures (HSF) mission office. HSF expands what is technically possible by developing approaches that will remove the scientific and technological limitations that stymie progress towards the healthcare of the future. HSF supports cutting-edge, often disease-agnostic research programs that have the potential for translational real-world change. Solution summary submissions must be submitted to: https://solutions.arpa-h.gov Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/ Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/ Amendment 3 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the prior solicitation(s) will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The following updates were made to the proposal documents: 1) Administrative & National Policy Requirements Document Updated the instructions and references within the “Organizational Conflicts of Interest (OCI) Affirmations and Disclosure” section. Updated questions, instructions, and content within the “Research Security Disclosure” section. Updated the instructions and intellectual property data assertions charts within the “IP” section. This included providing definitions of rights categories (unlimited, government purpose, limited, and specially negotiated/other) and consolidating two data assertions charts into one to assist proposers more efficiently complete the document. Specifically, the “Non-Commercial” and “Commercial” tables were removed and replaced with the “Background IP and Data Assertions” table. Eliminated the “Software Component Standards” section. Updated the Human Subjects Research (HSR) table…
Versions on SAM.gov
Source: SAM.gov Contract Opportunities public data file
Posted Jan 8, 2026SolicitationCurrent version
Respond by Mar 5, 2029, 11:59 PM UTC−5
This version on SAM.gov (opens SAM.gov in a new tab)Posted Nov 13, 2025Solicitation
Respond by Mar 5, 2029, 11:59 PM UTC−5
Changed from the version before: Description
This version on SAM.gov (opens SAM.gov in a new tab)Posted Oct 14, 2025Solicitation
Respond by Mar 5, 2029, 11:59 PM UTC−5
This version on SAM.gov (opens SAM.gov in a new tab)Posted Oct 14, 2025Solicitation
Respond by Mar 5, 2029, 11:59 PM UTC−5
Changed from the version before: Description
This version on SAM.gov (opens SAM.gov in a new tab)Posted Jun 6, 2025Solicitation
Respond by Mar 5, 2029, 11:59 PM UTC−5
Changed from the version before: Title, Response date, Description
This version on SAM.gov (opens SAM.gov in a new tab)